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Yes, but the rate seems to differ depending on the incarnation. The Second Doctor at one point developed grey hair ("The Two Doctors"); the Third Doctor noticeably aged between "Spearhead from Space" and "Planet of the Spiders", as did the Fourth Doctor between "Robot" and "Logopolis". However the Eleventh Doctor is known to have survived more than 200 years (per "The Impossible Astronaut", et al.) yet looks more or less the same as he did in "The Eleventh Hour", however he did very clearly age during his 900 years on Trenzalore in "The Time of the Doctor", also the Eighth Doctor visibly aged between "Doctor Who" and "The Night of the Doctor", as did the War Doctor between then and "The Day of the Doctor".