- Katarina died in "The Daleks' Master Plan".
- Sara Kingdom also died in "The Daleks' Master Plan".
- Adric died in "Earthshock".
- Grace Holloway died in "Doctor Who" (the telemovie), but was then resurrected.
- Jack Harkness first died in "The Parting of the Ways", then was resurrected, then died and was resurrected lots of times more.
- Amy Pond and Rory Williams were transferred to the past and died of old age in "The Angels Take Manhattan".
Apart from them, at least five individuals were asked to join to the Doctor's travels, but died before they were able to do so: Lynda Moss, Astrid Peth, Jenny (the Doctor's artificially generated daughter, who revived after the TARDIS had left), Rita and the Victorian Clara Oswald.