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She was taken to 1969 by the Silence, where they brainwashed her into wanting to kill the Doctor. They then put her in a spacesuit in order to sustain her with its life support system, and that's when she met the Doctor, Amy, Rory, and River (as seen in "The Impossible Astronaut"). After her spacesuit is shot by Amy, she escapes it and flees. Six months later, we see her regenerating in New York ("Day of the Moon"). She then becomes Mels, and grows up alongside Amy and Rory in the 1990s. She lives normally for a while, and in 2011, she follows Amy and Rory to a wheat field where they leave a message for the Doctor, and joins them on the TARDIS, which crash lands in 1938 Berlin due to Mels shooting the console. It is in Hitler's office that she is shot by him and regenerates in River Song ("Let's Kill Hitler").